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Published on: February 11, 2022
Mitral valve prolapse in adolescent female with hyperthyroidism
Elliot Griffith1, Eva Nunlist1,2
1Nemours Cardiac Center, Nemours Children's Hospital, Orlando, FL, United States of America.
Hyperthyroidism is often overlooked in young females with mitral valve prolapse. Early diagnosis is key, as subtle cardiac changes on echocardiography can indicate this thyroid condition.
Area of Science:
- Cardiology
- Endocrinology
- Medical Diagnostics
Background:
- Mitral valve prolapse (MVP) affects ~6% of young healthy females.
- MVP is 2-3 times more prevalent in hyperthyroidism patients.
- Hyperthyroidism can be difficult to diagnose early without classic symptoms.
Observation:
- A case report of an adolescent female presenting with palpitations and chest pain.
- Subtle mitral valve prolapse and trivial mitral regurgitation were observed on echocardiogram.
- The patient was diagnosed with hyperthyroidism.
Findings:
- Hyperthyroidism is often missed in patients with MVP.
- Echocardiographic findings can be subtle in early hyperthyroidism.
- Cardiac changes associated with hyperthyroidism are reviewed.
Implications:
- Highlights the importance of considering hyperthyroidism in young females with MVP.
- Suggests echocardiography may reveal subtle signs of hyperthyroidism.
- Emphasizes early diagnosis for better patient outcomes.
Related Concept Videos
Mitral Valve Prolapse I: Introduction
Mitral Valve Prolapse II: Assessment and Management
Mitral Valve Prolapse III: Nursing Management
Mitral Stenosis I: Introduction
Mitral Stenosis II: Clinical features and Diagnostic Tests
Mitral Stenosis III: Medical Management

