[MICROBIAL MARKERS OF CHRONIC CATARAL GINGIVITIS IN TREATMENT OF CHILDREN WITH FIXED ORTHODONTIC APPARATUS]

A side effect of treating children with fixed orthodontic equipment (FOE) is the deterioration of the oral microbiota and, as a typical consequence, a significant increase in the risk of chronic catarrhal gingivitis (CCG). The problem is to calculate the specified risk for each specific child, and its modern solution using models subjected to the machine learning procedure requires the identification of microbial and other markers of the process of formation of oral microbiota in the presence of FOE in healthy children and children with CCG. The identification of such markers was the main goal of this study. The experiment consisted in monitoring this process by four dental and nineteen microbial parameters at the third, sixth and twelfth month of orthodontic treatment of 30 non-sick and 32 patients with CCG having healthy periodontal tissues before the FOE. Markers were detected by correlation, principal component (PCA), factor and cluster analyzes of the obtained experimental data. As a result, a marker rating of the studied microbial and dental parameters was built, and most importantly, it was shown that the microorganisms Veillonella spp., Neisseria spp., Lactobacillus spp., Enterobacteriaceae spp. and some others have pronounced properties of markers of the process of formation of oral microbiota in the presence of FOE in healthy children and children with CCG.