Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Osteitis caused by BCG vaccination.

I Marík1, R Kubát, J Filipský

  • 1Orthopaedic Clinic, Paediatric Faculty, Prague, Czechoslovakia.

Journal of Pediatric Orthopedics
|May 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Treatment of children scoliosis by corrective brace with regulated force effect.

Journal of musculoskeletal & neuronal interactions·2011
Same author

[Arthrogryposis Multiplex Congenita - Part II.].

Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca·2010
Same author

[Flexional adduction contracture of the thumbs in distal arthrogryposis type I.].

Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca·2010
Same author

[Arthrogryposis multiplex congenita. I.].

Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca·2010
Same author

Biomechanics of leg deformity treatment.

Journal of musculoskeletal & neuronal interactions·2008
Same author

Hajdu-Cheney syndrome: report of a family and a short literature review.

Australasian radiology·2006
Same journal

Response to "Intraoperative Duplex Ultrasonography in the Pink Pulseless Hand: A Useful Adjunct, But Not Yet a Decision-Making Standard".

Journal of pediatric orthopedics·2026
Same journal

Pediatric Nonscaphoid Carpal Fractures: Fracture Distribution and Operative Management in an Institutional Cohort and 2 National EHR Databases.

Journal of pediatric orthopedics·2026
Same journal

Osteosynthesis With Barrel-Bone Grafting Technique for Failed Recalcitrant Cases of Congenital Pseudarthrosis of Tibia: Outcomes and Complications in a Series of 17 Patients.

Journal of pediatric orthopedics·2026
Same journal

The Relationship Between Screw Placement and Southwick Angle Remodeling in Slipped Capital Femoral Epiphysis.

Journal of pediatric orthopedics·2026
Same journal

Characteristics of Hip Dysplasia in Adults With Cerebral Palsy.

Journal of pediatric orthopedics·2026
Same journal

Long-term Follow-up of Myelomeningocele Patients: Factors That Can Affect Their Walking Ability.

Journal of pediatric orthopedics·2026
See all related articles

BCG osteitis in children, a bone infection caused by bacillus Calmette-Guerin (BCG) Mycobacterium bovis, was diagnosed in 26 Czechoslovakian children. This bone infection occurred approximately 17 months post-vaccination, with the proximal tibial end, distal femur, and proximal humerus most affected.

Area of Science:

  • Pediatric Infectious Diseases
  • Bacteriology
  • Skeletal System Pathology

Background:

  • BCG vaccination is obligatory in Czechoslovakia since 1953.
  • A new BCG vaccine introduced in 1980 led to an increase in BCG osteitis diagnoses starting in 1981.
  • BCG osteitis is a rare but serious complication of BCG vaccination.

Purpose of the Study:

  • To present a survey of BCG osteitis cases in Czechoslovakian children.
  • To describe the clinical presentation, diagnosis, and treatment of BCG osteitis.
  • To discuss the risks associated with BCG vaccination and potential strategies for prevention.

Main Methods:

  • Retrospective survey of 26 children diagnosed with BCG osteitis between 1981-1986.
  • Mycobacterial cultures were performed in 19 cases.

Related Experiment Videos

  • Analysis of vaccination details, symptomatology, and treatment outcomes.

    • Main Results:

    • BCG osteitis was confirmed in nine cases by Mycobacterium bovis culture.
    • Symptoms typically appeared 17 months after vaccination.
    • The proximal tibial end, distal femur, and proximal humerus were the most commonly affected skeletal sites.

    Conclusions:

    • The introduction of a new BCG vaccine in 1980 correlated with an increase in BCG osteitis cases.
    • Early diagnosis and appropriate treatment are crucial for managing BCG osteitis.
    • Consideration of alternative vaccination schedules, such as later-age vaccination, may reduce the risk of complications.