Related Experiment Video

Updated: Dec 10, 2025

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
08:41

Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2

Published on: November 5, 2021

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Coronavirus Disease - 2019-nCoV (COVID-19)

Linda Washington-Brown1, Rose Cirilo2

  • 1Broward College, Miramar Town Center, 2050 Civic Center Place, Miramar, FL 33025 Lbrown12313@yahoo.com.

Journal of National Black Nurses' Association : JNBNA
|August 28, 2020
PubMed

Insights

Coronaviruses are zoonotic viruses causing illnesses from colds to severe respiratory infections. High-risk groups include the elderly, immunocompromised, and frontline workers, necessitating preparedness for outbreaks.

Area of Science:

  • Virology
  • Public Health

Background:

  • Coronaviruses are a large family of zoonotic viruses causing various illnesses.
  • The name 'coronavirus' derives from the Latin word 'corona' for crown, due to their crown-like surface spikes.
  • The World Health Organization (WHO) identifies coronaviruses as a significant public health concern.

Purpose of the Study:

  • To define coronaviruses and identify populations at high risk for severe illness.
  • To emphasize the importance of preparedness for healthcare and essential workers.

Main Methods:

  • Literature review of World Health Organization (WHO) reports and relevant studies.
  • Identification of at-risk populations based on age, health status, occupation, and travel history.

Main Results:

  • Coronaviruses can cause mild to severe lower respiratory tract infections (LRTIs).
  • High-risk groups include young children, older adults, individuals with comorbidities (cardiac, respiratory), and the immunocompromised.
  • Healthcare workers, essential community workers, those with close contact, and recent travelers to affected regions are also at increased risk.

Conclusions:

  • The potential community health risk of coronaviruses, including 2019-nCoV, is significant.
  • Preparedness and knowledge among frontline workers are crucial for managing global outbreaks.

Keywords:
2019-nCoVCOVID19coronavirusglobal outbreaknovel SARS-CoV-2

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