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Catheter-Directed Thrombolysis of Iliocaval Thrombosis in Patients With COVID-19 Infection
Mohamad Al-Otaibi1, Omer Iftikhar2, Yevgeniy Brailovsky3
1Department of Internal Medicine, Temple University Hospital, Philadelphia, Pennsylvania.
JACC. Case Reports
|September 1, 2020
Insights
Catheter-directed thrombolysis effectively treated iliocaval thrombosis in two patients with coronavirus disease (COVID-19). This minimally invasive procedure demonstrated positive outcomes for these complex cases.
Area of Science:
- Vascular Medicine
- Interventional Cardiology
- Critical Care Medicine
Background:
- Coronavirus disease 2019 (COVID-19) is associated with an increased risk of thrombotic events.
- Iliocaval thrombosis is a severe complication that can occur in critically ill patients with COVID-19.
Observation:
- This report details the first two cases of catheter-directed thrombolysis (CDT) for COVID-19-related iliocaval thrombosis.
- Both patients presented with extensive thrombus burden and significant symptoms.
Findings:
- Catheter-directed thrombolysis was successfully performed in both patients.
- The procedure resulted in significant thrombus resolution and clinical improvement.
- No major procedural complications were observed.
Implications:
- Catheter-directed thrombolysis is a viable and effective treatment option for iliocaval thrombosis in COVID-19 patients.
- This approach may help reduce morbidity and mortality associated with severe COVID-19-related venous thromboembolism.
- Further research is warranted to establish optimal protocols and long-term outcomes.
Abstract:
We present the characteristics and outcomes of the first 2 cases of catheter-directed thrombolysis performed in patients presenting with coronavirus disease-2019 (COVID-19)-related iliocaval thrombosis. (Level of Difficulty: Beginner.).
Keywords:
BEC, Bashir endovascular catheterCDT, catheter-directed thrombolysisCFV, common femoral veinCOVID-19 infectionCOVID-19 infection complicationCOVID-19, coronavirus disease-2019DVT, deep vein thrombosisEIV, external iliac veinIVC, inferior vena cavaLMWH, low-molecular-weight heparinPV, popliteal veinSARS-CoV-2, severe acute respiratory syndrome-associated coronavirus-2clot burdendeep vein thrombosisfemoral vein thrombosisrtPA, recombinant tissue plasminogen activator
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