Related Experiment Video
Updated: Dec 10, 2025
06:13
Endoscopic Septoplasty with Limited Two-line Resection: Minimally Invasive Surgery for Septal Deviation
Published on: June 20, 2018
17.5K
Olfactory changes after endoscopic sinus surgery for chronic rhinosinusitis: A meta-analysis.
Rui Zhao1,2, Kai Chen1, Yuedi Tang1
1Department of Otorhinolaryngology, West China Hospital of Sichuan University, Chengdu, China.
Summary
Endoscopic sinus surgery (ESS) may improve olfaction in chronic rhinosinusitis (CRS) patients, particularly those with nasal polyps. However, benefits for CRS without polyps were not significant, warranting further research.
Area of Science:
- Otolaryngology
- Rhinology
- Olfactory Research
Background:
- Chronic rhinosinusitis (CRS) is a prevalent condition affecting quality of life.
- Endoscopic sinus surgery (ESS) is a common treatment for CRS, but its impact on olfaction is debated.
- Olfactory dysfunction is a significant symptom in many CRS patients.
Purpose of the Study:
- To systematically evaluate the effect of ESS on olfactory function in patients diagnosed with CRS.
- To synthesize existing evidence through a meta-analysis to determine the overall impact of ESS on smell.
- To differentiate the olfactory outcomes of ESS based on CRS subtypes, such as those with and without nasal polyps.
Main Methods:
- A comprehensive meta-analysis was performed.
- Systematic literature searches were conducted across PubMed, EMBASE, and Cochrane Library databases.
- Studies assessing olfactory changes post-ESS in CRS patients using validated smell tests were included and analyzed.
Main Results:
- Thirty-five studies with 3164 patients were included.
- ESS showed significant improvement in olfaction for CRS patients with nasal polyps across multiple validated tests.
- Olfactory improvements were also noted in non-classified CRS patients, but not consistently in CRS patients without nasal polyps.
Conclusions:
- Endoscopic sinus surgery appears to offer benefits for olfactory improvement in certain chronic rhinosinusitis patient groups, especially those with nasal polyps.
- The effectiveness of ESS on olfaction varies depending on the presence of nasal polyps.
- Further rigorous studies are recommended to fully elucidate the olfactory impact of ESS in CRS.
More Related Videos
Related Concept Videos
01:03Olfactory Receptors: Location and Structure
10.9K
The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
10.9K
01:29Suctioning the Nasopharyngeal Airway
2.2K
Nasopharyngeal suctioning is a procedure to remove secretions from the upper part of the respiratory tract that the patient cannot clear independently. It helps maintain airway patency and prevents complications such as aspiration pneumonia.
Equipment Required
Equipment Required
2.2K
01:30Epistaxis
411
Epistaxis, or nosebleeds, occurs when small, swollen blood vessels in the nasal mucous membrane rupture. Typically, the anterior septum is the primary site of occurrence.
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
411
01:24Nose and Nasal Cavity
8.6K
The nose is composed of an observable exterior segment (external nose) and an internal segment within the skull known as the nasal cavity (internal nose). The external nose, visible on the face, consists of a framework of bone and hyaline cartilage enveloped in skin and muscle and lined with a mucous membrane. This structure is supported by the frontal bone, nasal bones, and maxillary bone and is supplemented by a cartilaginous framework comprising the septal nasal cartilage, lateral nasal...
8.6K