Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Tumor Immunotherapy01:27

Tumor Immunotherapy

1.4K
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
1.4K
The Tumor Microenvironment02:17

The Tumor Microenvironment

7.4K
Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
7.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of body mass index on outcomes after radical cystectomy: A retrospective Australian cohort study.

BJUI compass·2026
Same author

A Growing Mortality Divide: Demographic and Regional Disparities in Cirrhosis With Renal Failure, U.S. 1999-2023.

Journal of immigrant and minority health·2026
Same author

Future Considerations When Considering Partial Thymectomy.

The Annals of thoracic surgery·2026
Same author

Initial experience with transcatheter aortic valve replacement before and after lung transplant.

JTCVS structural and endovascular·2026
Same author

Less May Be Enough: Clinical Equipoise for Partial Thymectomy.

The Annals of thoracic surgery·2026
Same author

Reply: Timing, risk, and relevance: Refining venous thromboembolism screening in esophageal cancer.

The Journal of thoracic and cardiovascular surgery·2026

Related Experiment Video

Updated: Dec 10, 2025

Isolation and Transplantation of Different Aged Murine Thymic Grafts.
05:47

Isolation and Transplantation of Different Aged Murine Thymic Grafts.

Published on: May 13, 2015

14.3K

Thymic Malignancy-Updates in Staging and Management.

Jesse M P Rappaport1, James Huang2, Usman Ahmad3

  • 1Department of Cardiothoracic Surgery, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, OH, USA.

Surgical Oncology Clinics of North America
|September 5, 2020
PubMed
Summary
This summary is machine-generated.

Thymomas and thymic carcinomas require tailored treatment. Complete resection is key for early stages, while multimodal therapy, including neoadjuvant approaches, is vital for advanced thymic tumors.

Keywords:
ChemoradiationChemotherapyMultimodal therapyNeoadjuvantThymic carcinomaThymoma

More Related Videos

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
03:55

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

831
Derivation of Thymic Lymphoma T-cell Lines from Atm-/- and p53-/- Mice
17:59

Derivation of Thymic Lymphoma T-cell Lines from Atm-/- and p53-/- Mice

Published on: April 3, 2011

12.6K

Related Experiment Videos

Last Updated: Dec 10, 2025

Isolation and Transplantation of Different Aged Murine Thymic Grafts.
05:47

Isolation and Transplantation of Different Aged Murine Thymic Grafts.

Published on: May 13, 2015

14.3K
Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
03:55

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

831
Derivation of Thymic Lymphoma T-cell Lines from Atm-/- and p53-/- Mice
17:59

Derivation of Thymic Lymphoma T-cell Lines from Atm-/- and p53-/- Mice

Published on: April 3, 2011

12.6K

Area of Science:

  • Oncology
  • Thoracic Surgery

Background:

  • Thymomas are generally indolent but can present as locally advanced disease.
  • Thymic carcinoma exhibits aggressive behavior with poor survival outcomes.

Purpose of the Study:

  • To review management strategies for thymomas and thymic carcinomas.
  • To identify prognostic factors for long-term survival in thymic malignancies.

Main Methods:

  • Review of current literature on thymoma and thymic carcinoma management.
  • Analysis of treatment outcomes based on tumor stage and resection status.

Main Results:

  • Complete resection is optimal for early-stage thymomas.
  • Multimodal therapy, potentially including neoadjuvant treatment, is standard for locally advanced thymic tumors.
  • Tumor stage and complete resection significantly impact long-term survival.

Conclusions:

  • Effective management of thymic malignancies depends on stage and resectability.
  • Current targeted and immunotherapies show limited efficacy in advanced thymic cancers.