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Updated: Dec 9, 2025

Assessment of Intestinal Transcytosis of Neonatal Escherichia coli Bacteremia Isolates
Published on: February 17, 2023
Occult Bacteremia in Young Children with Very High Fever Without a Source: A Multicenter Study
Iker Gangoiti1, Ane Zubizarreta, Borja Elgoibar
1Pediatric Emergency Department, Biocruces Bizkaia Health Research Institute, Hospital Universitario Cruces, University of the Basque Country, UPV/EHU, Bilbao, Basque Country, Spain.
Abstract:
We carried out a prospective multicenter study including 203 previously healthy well-appearing children who were 3-24 months old with fever without a source ≥40.5°C. Thirty-one (15.3%, 95% confidence interval 11.0-20.9) were diagnosed with serious bacterial infection, including 6 with bacteremia (3%, 95% confidence interval 1.4-6.3). Testing for occult bacteremia in children 3-24 months old with fever without a source should be considered when fever at ≥40.5°C.
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