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Updated: Dec 9, 2025

Chronic Post-Ischemia Pain Model for Complex Regional Pain Syndrome Type-I in Rats
Published on: January 21, 2020
Orofacial complex regional pain syndrome
Mythili Kalladka1, Hussein Alhasan1, Nagaraju Morubagal2
1Orofacial Pain and Temporomandibular Disorders, Eastman Institute for Oral Health.
Abstract:
Complex regional pain syndrome (CRPS)-an extremely painful primary pain disorder related to trauma-is rare in the orofacial region. The authors describe a case of orofacial CRPS with a clinical phenotype that fits the Budapest diagnostic criteria. A 39-year-old female patient presented with left-side facial pain that had been untreated for 10 months. Symptoms included burning pain and allodynia accompanied by swelling and redness on exposure to cold or stress. The diagnosis was confirmed after stellate ganglion anesthetic block resulted in substantial improvement.
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