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Association of Childhood Atopic Dermatitis With Atopic and Nonatopic Multimorbidity

Brian T Cheng1, Nanette B Silverberg2, Jonathan I Silverberg3

  • 1From the Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, IL.

Dermatitis : Contact, Atopic, Occupational, Drug
|September 10, 2020
PubMed

Insights

Childhood atopic dermatitis (AD) is linked to more chronic health conditions. Identifying atopic disease in children with AD can help manage these co-occurring conditions.

Area of Science:

  • Pediatric Dermatology
  • Epidemiology
  • Chronic Disease Management

Background:

  • The impact of multimorbidity on childhood atopic dermatitis (AD) is not well understood.
  • Childhood AD requires further investigation regarding associated chronic health conditions.

Purpose of the Study:

  • To determine the prevalence and predictors of chronic disease multimorbidity in children diagnosed with atopic dermatitis.
  • To investigate the association between AD severity and multimorbidity in pediatric populations.

Main Methods:

  • Utilized data from the 1996-2015 Medical Expenditure Panel Survey, a representative sample of US households.
  • Assessed multimorbidity using the Charlson Comorbidity Index (CCI) and Healthcare Utilization Project Chronic Comorbidity Indicator (HCUP-CCI).
  • Analyzed the frequency of atopic comorbidities in children with and without AD.

Main Results:

  • Children with mild-moderate and severe AD exhibited higher CCI and HCUP-CCI scores compared to controls.
  • The presence of atopic disease alongside AD significantly increased CCI and HCUP-CCI scores.
  • Young children and adolescents with AD experienced a greater number of atopic comorbidities.

Conclusions:

  • Pediatric atopic dermatitis is associated with a higher burden of both atopic and non-atopic multimorbidity.
  • Children with AD and comorbid atopic conditions represent a distinct group that may benefit from targeted screening and management strategies for multimorbidity.
Abstract

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