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Design of Surface Enhanced Raman Scattering (SERS) Nanosensor Array
Yaakov Mandelbaum1, Raz Mottes1, Zeev Zalevsky2,3
1Advanced Laboratory of Electro-Optics (ALEO), Department of Applied Physics/Electro-Optics Engineering, Lev Academic Center, 9116001 Jerusalem, Israel.
Sensors (Basel, Switzerland)
|September 11, 2020
Summary
Researchers developed an advanced Surface-Enhanced Raman Scattering (SERS) nanosensor array for real-time pH imaging. This pH imager enables spatially resolved chemical measurements, crucial for monitoring reactions.
Area of Science:
- Nanotechnology
- Chemical Sensing
- Spectroscopy
Background:
- Real-time chemical reaction monitoring is essential.
- Existing pH measurement methods lack spatial resolution.
- Advanced nanosensor arrays offer potential for improved chemical imaging.
Purpose of the Study:
- To present an advanced Surface-Enhanced Raman Scattering (SERS) nanosensor array.
- To develop a future pH imager for real-time chemical reaction detection.
- To enable spatially resolved pH measurements in fluid targets.
Main Methods:
- Design and simulation of a SERS pixel array.
- Fabrication of nanostructured substrates with projections or cavities.
- Structural characterization using Focused Ion Beam (FIB), Transmission Electron Microscopy (TEM), and Scanning Electron Microscopy (SEM).
- Optimization of nanostructure shape and metallic layer thickness (Ag or Au) for maximal enhancement.
Main Results:
- Demonstration of an advanced SERS pixel array.
- Preliminary experimental results confirming structural characteristics.
- Capability for spatially resolved pH measurements in fluid targets.
- Tuning of nanostructures and metallic layers for desired wavelength enhancement.
Conclusions:
- The developed SERS nanosensor array is a promising platform for pH imaging.
- The array architecture allows for optimized responsivity through nanostructure arrangement.
- This technology paves the way for real-time monitoring of chemical reactions.

