Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Multiomic Analysis Reveals an IFN-driven Cellular Landscape Effectively Targeted by Ruxolitinib in Hailey-Hailey Disease.

bioRxiv : the preprint server for biology·2026

Same author

Improving the Severity Classification System of Diabetes-Related Foot Infections: Necrosis is a Better Predictor of Amputation Than Systemic Inflammatory Response.

Foot & ankle specialist·2026

Same author

CARMN fusions and PDGFRB mutations highlight key differences among cutaneous tumors with myopericytic differentiation.

The Journal of investigative dermatology·2026

Same author

Updates in Skin Adnexal Tumors.

Dermatologic clinics·2026

Same author

Single-cell and spatial profiling reveal cDC2A-CXCL13<sup>+</sup>CD8<sup>+</sup> T-epithelial cell crosstalk and cytotoxicity through TNFRSF9 in cutaneous and mucosal lichen planus.

Nature communications·2026

Same author

Do Immediate Perioperative Glucose Measurements Predict Outcomes in Non-Elective Pedal Amputation?

Foot & ankle specialist·2026

Same journal

Tourniquet Use Does Not Affect Soft Tissue Outcomes Following Rotational Ankle Fracture Repair.

Foot & ankle specialist·2026

Same journal

Concentrated Bone Marrow Aspirate in the Management of Foot and Ankle Pathologies.

Foot & ankle specialist·2026

Same journal

Early Clinical Outcomes of a Novel Synthetic Augmentation Device (TEKBRACE) in Ankle Ligament Repair: A Case Series.

Foot & ankle specialist·2026

Same journal

Functional Outcomes of Displaced Intra-Articular Calcaneal Fractures: A Randomized Superiority Trial of Essex-Lopresti Versus 3-Point Distraction Technique by Forgon and Zadravecz.

Foot & ankle specialist·2026

Same journal

Multicenter Treatment of Ankle Fractures: Does Arthroscopic Examination Make a Difference?

Foot & ankle specialist·2026

Same journal

Comparison of Spinal Anesthesia and Wide-Awake Local Anesthesia No Tourniquet in Hallux Valgus Surgery.

Foot & ankle specialist·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Dec 9, 2025

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Published on: August 18, 2022

Eccrine Porocarcinoma: Avoiding Diagnostic Delay.

Christine Jarocki¹, Jeffery Kozlow², Paul W Harms^3,4

¹Department of Internal Medicine, Division of Metabolism, Endocrinology, and Diabetes, University of Michigan Health System, Ann Arbor, Michigan.

Foot & Ankle Specialist

|September 14, 2020

Summary

This summary is machine-generated.

Eccrine porocarcinoma, a rare skin cancer, often mimics benign lesions, leading to diagnostic delays. Early recognition and a multispecialty approach are crucial for managing this aggressive sweat gland cancer.

Keywords:

lymphoscintigraphy metastasis multispecialty skin cancer

More Related Videos

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Author Spotlight: Reprogramming Cancer Cells to iPSCs to Study Disease Progression and Treatment Targets

Author Spotlight: Reprogramming Cancer Cells to iPSCs to Study Disease Progression and Treatment Targets

Published on: February 2, 2024

Related Experiment Videos

Last Updated: Dec 9, 2025

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Published on: August 18, 2022

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Author Spotlight: Reprogramming Cancer Cells to iPSCs to Study Disease Progression and Treatment Targets

Author Spotlight: Reprogramming Cancer Cells to iPSCs to Study Disease Progression and Treatment Targets

Published on: February 2, 2024

Area of Science:

Oncology
Dermatopathology
Cutaneous Neoplasms

Background:

Skin cancer is highly prevalent in the US, affecting 1 in 5 Americans.
Eccrine porocarcinoma, a rare sweat gland cancer, typically presents on lower extremities.
Clinical presentation can mimic benign skin lesions, complicating diagnosis.

Purpose of the Study:

To report a case of eccrine porocarcinoma with a significant diagnostic delay.
To highlight diagnostic challenges and the importance of high-risk cancer detection.
To discuss a multispecialty treatment approach for eccrine porocarcinoma.

Main Methods:

Case report with 22 months of follow-up.
Review of diagnostic delays across primary care, dermatology, and wound therapy.
Discussion of management strategies for suspected high-risk cutaneous cancers.

Main Results:

A multiyear delay in diagnosis was observed.
The case underscores the need for vigilance in evaluating suspicious skin lesions.
A comprehensive, multispecialty treatment plan was implemented.

Conclusions:

Eccrine porocarcinoma requires a high index of suspicion due to its potential for metastasis.
Multispecialty collaboration is essential for timely diagnosis and effective management.
Improved diagnostic techniques are needed for rare cutaneous malignancies.