Recording EMT Activity by Lineage Tracing during Metastasis
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Updated: Dec 9, 2025

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Ex vivo Live Imaging of Lung Metastasis and Their Microenvironment
Published on: February 3, 2016
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Pauline Vieugué1, Cédric Blanpain1
1Laboratory of Stem Cells and Cancer, WELBIO, Université Libre de Bruxelles (ULB), 808 route de Lennik, Bat GE, G2 4.205, 1070 Bruxelles, Belgium.
Developmental Cell
|September 15, 2020
Abstract:
In this issue of Developmental Cell, Li et al. develop a novel lineage tracing system to record EMT activity during lung metastasis of mammary tumors. Using EMT-tracer mouse models, they reveal that N-cadherin is transiently expressed by most metastasis-initiating cells and demonstrate its functional importance during the metastatic cascade.

