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Model-based reconstruction for simultaneous multi-slice mapping using single-shot inversion-recovery radial FLASH.

Xiaoqing Wang1,2, Sebastian Rosenzweig1,2, Nick Scholand1,2

  • 1Institute for Diagnostic and Interventional Radiology, University Medical Center Göttingen, Göttingen, Germany.

Magnetic Resonance in Medicine
|September 16, 2020
PubMed
Summary
This summary is machine-generated.

This study introduces a fast, multi-slice mapping technique using simultaneous multi-slice (SMS) excitations and model-based reconstruction. The method achieves accurate and repeatable measurements in the brain and liver, significantly reducing scan times.

Keywords:
model-based reconstructionradial FLASHsimultaneous multi-slice

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Area of Science:

  • Magnetic Resonance Imaging (MRI)
  • Medical Physics

Background:

  • Quantitative mapping is crucial for various MRI applications.
  • Current multi-slice mapping methods can be time-consuming.
  • Simultaneous Multi-Slice (SMS) techniques offer accelerated data acquisition.

Purpose of the Study:

  • To develop a novel single-shot, multi-slice mapping method.
  • To combine Simultaneous Multi-Slice (SMS) excitations with single-shot inversion-recovery (IR) radial fast low-angle shot (FLASH) sequences.
  • To implement a nonlinear model-based reconstruction for improved parameter estimation.

Main Methods:

  • Extended a single-slice calibrationless model-based reconstruction to SMS.
  • Formulated parameter map and coil sensitivity estimation as a single nonlinear inverse problem.
  • Applied joint-sparsity constraints for enhanced precision.
  • Validated the method in phantoms and human brain/liver scans.

Main Results:

  • Achieved accurate and precise multi-slice maps comparable to single-slice references.
  • Demonstrated superior performance of SMS over conventional interleaved acquisitions in brain scans.
  • Confirmed good accuracy, precision, and repeatability in 6 healthy subjects (brain and abdomen).
  • Enabled rapid acquisition of 5 brain slices or 3 abdominal slices in 4 seconds.

Conclusions:

  • The proposed IR SMS radial FLASH method enables rapid, high-resolution multi-slice mapping.
  • The technique offers good accuracy, precision, and repeatability.
  • This advancement has potential for accelerated quantitative MRI.