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Updated: Dec 8, 2025

Author Spotlight: A 3D Digital Model for the Diagnosis and Treatment of Pulmonary Nodules

Author Spotlight: A 3D Digital Model for the Diagnosis and Treatment of Pulmonary Nodules

Published on: May 19, 2023

Subsolid pulmonary nodules: Controversy and perspective.

Mark M Hammer¹, Hiroto Hatabu¹

¹Departments of Radiology, Brigham and Women's Hospital, Boston, MA, USA.

European Journal of Radiology Open

|September 18, 2020

Summary

This summary is machine-generated.

Management of subsolid nodules, including ground glass and part-solid types, is evolving. Current evidence suggests less aggressive treatment and individualized follow-up strategies for these potentially malignant but indolent lung nodules.

Keywords:

Ground glass nodule Part-solid nodule Subsolid nodule

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Area of Science:

Pulmonology
Thoracic Oncology
Radiology

Background:

Subsolid nodules (SSNs), encompassing ground glass and part-solid nodules, pose diagnostic and management challenges.
While SSNs carry a risk of malignancy, they often exhibit indolent behavior when cancerous.
Current clinical practice for SSNs requires refinement to balance malignancy risk with indolent tumor biology.

Purpose of the Study:

To review emerging data on the management of subsolid nodules.
To evaluate the appropriateness of extended follow-up intervals and reduced follow-up duration for SSNs.
To assess the trend towards less aggressive therapeutic interventions for SSNs.

Main Methods:

Review of current literature and emerging data regarding subsolid nodule management.
Analysis of trends in follow-up protocols for ground glass and part-solid nodules.
Evaluation of shifts in definitive treatment strategies for malignant SSNs.

Main Results:

Emerging data support longer intervals and shorter overall duration for SSN follow-up.
Malignant SSNs often display indolent growth patterns, justifying less aggressive surveillance.
Definitive therapy is increasingly favoring less invasive options, such as sub-lobar resection.

Conclusions:

Individualized management approaches for subsolid nodules are recommended.
Patient-specific and imaging features should guide decisions on the necessity of treatment.
Optimized surveillance and treatment strategies can improve patient outcomes while minimizing overtreatment.