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Updated: Dec 8, 2025

Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis
Published on: February 10, 2023
Heterotopic ossification with femoral vein compression mimicking deep vein thrombosis
Cheng-Yu Ko1, Hung-Kai Weng2, Ping-Yen Liu1,3
1Division of Cardiology, Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Abstract:
Heterotopic ossification (HO) in patients with spinal cord injury could lead to local tissue swelling and sometimes mimic the clinical presentation of deep vein thrombosis. Recognition and effective management is critical. We report the case of a bedridden patient with spinal cord injury presenting with diffuse right lower limb swelling caused by external venous compression from HO. The patient underwent surgery and local radiation therapy. Postoperative venography disclosed a marked improvement in the blood flow, and symptoms were alleviated. We discuss the role of venography in the diagnosis and treatment of venous compression in the setting of HO.
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