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Nutrition and immunity: I. Basic considerations. II. Practical applications.

R K Chandra

    ASDC Journal of Dentistry for Children
    |May 1, 1987
    PubMed
    Summary
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    Nutrition significantly impacts immune function, with deficiencies and excesses affecting immunity. Both malnutrition and obesity can compromise immune responses, highlighting the critical role of balanced nutrition for a healthy immune system.

    Area of Science:

    • Immunology
    • Nutritional Science
    • Public Health

    Background:

    • Nutrition and immunity are closely interconnected.
    • Nutritional status influences immune system components.
    • Early research focused on protein-energy malnutrition in children.

    Purpose of the Study:

    • To explore the intricate relationship between nutrition, immunity, and infection.
    • To review the effects of nutritional deficiencies and excesses on immune function.
    • To discuss practical applications of nutritional regulation of immunity.

    Main Methods:

    • Literature review of studies on nutrition and immunity.
    • Analysis of effects of protein-energy malnutrition.
    • Examination of single nutrient imbalances and their impact on immunocompetence.

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    Main Results:

    • Nutritional deficiencies (protein, amino acids, vitamins A, E, B6, folate, trace minerals) reduce immunocompetence.
    • Excessive intake of certain nutrients (fat, polyunsaturated fatty acids, iron, vitamin E) can be immunosuppressive.
    • Malnutrition, obesity, and infections all adversely affect immune function.

    Conclusions:

    • Both nutrient deficiencies and excesses can impair immune function.
    • Understanding nutritional regulation of immunity offers practical health applications.
    • Maintaining balanced nutrition is crucial for optimal immune responses.