Related Experiment Video
Updated: Dec 8, 2025

Monitoring Influenza Virus Survival Outside the Host Using Real-Time Cell Analysis
Published on: February 20, 2021
Time-dependent solution of the NIMFA equations around the epidemic threshold
Bastian Prasse1, Piet Van Mieghem2
1Faculty of Electrical Engineering, Mathematics and Computer Science, P.O Box 5031, 2600 GA, Delft, The Netherlands. b.prasse@tudelft.nl.
Abstract:
The majority of epidemic models are described by non-linear differential equations which do not have a closed-form solution. Due to the absence of a closed-form solution, the understanding of the precise dynamics of a virus is rather limited. We solve the differential equations of the N-intertwined mean-field approximation of the susceptible-infected-susceptible epidemic process with heterogeneous spreading parameters around the epidemic threshold for an arbitrary contact network, provided that the initial viral state vector is small or parallel to the steady-state vector. Numerical simulations demonstrate that the solution around the epidemic threshold is accurate, also above the epidemic threshold and for general initial viral states that are below the steady-state.
Related Concept Videos
Exponential Equations for Modeling Growth
Steps in Outbreak Investigation
Exponential Equations with Logarithms: Problem Solving
Determination of Multiple Dosing Parameters: Steady-State, Minimum and Maximum Concentrations
Poisson's And Laplace's Equation
Hazard Rate

