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Imaging of facial neuritis using T2-weighted gradient-echo fast imaging employing steady-state acquisition after
Magali Hector1, Ahmad Alnadji2, Francis Veillon2
1Service de Radiologie 1, Hôpital de Hautepierre, Hôpitaux Universitaires de Strasbourg, 1 Avenue Molière, 67200, Strasbourg, France. magali.hector67@gmail.com.
Background:
MRI is the modality of choice for the imaging of facial neuritis. Previously, gadolinium-enhanced T1-weighted imaging of the petrous bone, then FLAIR sequences were thought to be most informative for acute facial neuritis imaging. The aim of this study is to evaluate the value of contrast-enhanced T2-weighted sequence for the diagnosis of acute facial neuritis and compare it to contrast-enhanced T1-weighted and FLAIR sequences.
Methods:
We included 50 patients with an acute unilateral idiopathic peripheral facial neuritis. An MRI (3 T) with three sequences was performed (T1-weighted, T2-weighted and FLAIR), all acquired after intravenous contrast-media injection.
Results:
The contrast-enhanced T2-weighted sequence appeared to be the most accurate one for the diagnosis of acute facial neuritis (Se 94%, Sp 100%, accuracy 98.2%, p < 0.001), with a pathological facial nerve strongly (grade 2-3) enhancing and a homogenous enhancement along the course of the entire facial nerve. Contrast-enhanced T1-weighted (Se 80%, Sp 100%, accuracy 94.1%) and FLAIR sequences (92%, Sp 88%, accuracy 90%, p < 0.001) showed lower accuracy. On T1-weighted sequence, a strong enhancement (blurred margins) of the canalicular segment was observed in 80% of the cases when it was never observed in normal nerves.
Conclusion:
A strong (= iso to hyperintense to the petrous fat signal) and diffuse (all segments) enhancement of the facial nerve on T2-weighted steady-state free precession sequence is a sensitive and specific sign for the diagnosis of acute idiopathic facial neuritis, and appears superior to T1WI and FLAIR sequences.
Insights
Contrast-enhanced T2-weighted MRI sequences are highly accurate for diagnosing acute facial neuritis. This method offers superior sensitivity and specificity compared to T1-weighted and FLAIR sequences for facial nerve imaging.
Area of Science:
- Radiology
- Medical Imaging
- Neurology
Background:
- Magnetic Resonance Imaging (MRI) is crucial for diagnosing facial neuritis.
- Traditionally, gadolinium-enhanced T1-weighted and FLAIR sequences were used.
- This study investigates a novel approach using contrast-enhanced T2-weighted sequences.
Purpose of the Study:
- To evaluate the diagnostic value of contrast-enhanced T2-weighted MRI for acute facial neuritis.
- To compare its efficacy against contrast-enhanced T1-weighted and FLAIR sequences.
Main Methods:
- Fifty patients with acute unilateral idiopathic peripheral facial neuritis were included.
- All patients underwent a 3 Tesla MRI scan with T1-weighted, T2-weighted, and FLAIR sequences post-contrast injection.
Main Results:
- Contrast-enhanced T2-weighted imaging demonstrated the highest accuracy (98.2%) with 94% sensitivity and 100% specificity.
- Pathological facial nerves showed strong, homogeneous enhancement along their entire course.
- T1-weighted (94.1% accuracy) and FLAIR (90% accuracy) sequences showed lower diagnostic performance.
Conclusions:
- Strong and diffuse enhancement of the facial nerve on contrast-enhanced T2-weighted sequences is a key indicator of acute idiopathic facial neuritis.
- This sequence is more sensitive and specific than T1-weighted and FLAIR sequences for diagnosing facial neuritis.
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