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Association between relative hand-grip strength and chronic cardiometabolic and musculoskeletal diseases in Koreans:
Yoo Mee Kim1, Sunghoon Kim2, Jaehyun Bae1
1Division of Endocrinology and Metabolism, Department of Internal Medicine, Catholic Kwandong University College of Medicine, International St. Mary's Hospital, Incheon, South Korea.
Insights
Lower relative hand-grip strength (HGS) is linked to increased odds of chronic diseases in older adults. This convenient muscle strength measure may aid in early disease screening.
Area of Science:
- Gerontology
- Cardiology
- Metabolic Health
Background:
- Relative hand-grip strength (HGS) is a measure of muscle strength adjusted for body size.
- Aging is associated with declines in muscle mass and strength, impacting overall health.
- Chronic diseases pose a significant health burden on the elderly population.
Purpose of the Study:
- To evaluate clinical and cardiometabolic markers associated with relative HGS.
- To investigate the odds of chronic diseases based on relative HGS levels in older adults.
Main Methods:
- Cross-sectional study of 2451 Korean adults aged 50+ from the Korea National Health and Nutrition Examination Survey.
- Relative HGS calculated as absolute HGS divided by body mass index (BMI).
- Multivariate regression analyses used to assess associations between relative HGS tertiles and chronic disease prevalence.
Main Results:
- Relative HGS was associated with insulin resistance, high-sensitivity C-reactive protein, and HDL cholesterol.
- Lower relative HGS was linked to higher odds of various chronic diseases in both sexes.
- Higher odds of hyperlipidemia were observed in women with the lowest relative HGS.
Conclusions:
- Relative HGS is a practical indicator of overall muscle strength relative to body size.
- Low relative HGS may predict the development or worsening of chronic conditions.
- Relative HGS can serve as a cost-effective screening tool for prevalent chronic diseases in the elderly.
Objectives:
This study evaluated clinical and cardiometabolic markers associated with relative hand-grip strength (HGS), and investigated odds ratios (ORs) for chronic cardiometabolic and musculoskeletal diseases according to relative HGS.
Methods:
This cross-sectional observational study enrolled subjects from the Korea National Health and Nutrition Examination Survey who were 50 years and older (N = 2451). Information on chronic diseases was taken by individual surveys and other proper criteria were applied for undiagnosed subjects. Absolute HGS was calculated from the maximal bilateral HGS (kg) as measured by a dynamometer and relative HGS was calculated by dividing absolute HGS by body mass index (BMI). Associated clinical and cardiometabolic markers to relative HGS were investigated and ORs for chronic diseases according to relative HGS tertiles were estimated from multivariate linear or logistic regression analyses.
Results:
The mean relative HGS (kg/BMI) was 3.1 ± 0.6 for men and 1.9 ± 0.5 for women. Insulin-resistance parameters and high-sensitivity C-reactive protein were negatively and high-density lipoprotein cholesterol was positively related with relative HGS in both sexes adjusting for age and lifestyle factors, while systolic blood pressure showed negative relationship in women. High ORs for various chronic diseases were observed in the lowest relative HGS tertile of both sexes, but high OR for hyperlipidemia was observed only in women.
Conclusions:
Relative HGS is a convenient measure for overall muscle strength according to body size and may have an influence on chronic disease development or aggravation. Thus, relative HGS might be a cost-effective and useful tool to screen for prevalent chronic diseases in elderly population.
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