Association between relative hand-grip strength and chronic cardiometabolic and musculoskeletal diseases in Koreans:

Yoo Mee Kim1, Sunghoon Kim2, Jaehyun Bae1

  • 1Division of Endocrinology and Metabolism, Department of Internal Medicine, Catholic Kwandong University College of Medicine, International St. Mary's Hospital, Incheon, South Korea.

Insights

Lower relative hand-grip strength (HGS) is linked to increased odds of chronic diseases in older adults. This convenient muscle strength measure may aid in early disease screening.

Area of Science:

  • Gerontology
  • Cardiology
  • Metabolic Health

Background:

  • Relative hand-grip strength (HGS) is a measure of muscle strength adjusted for body size.
  • Aging is associated with declines in muscle mass and strength, impacting overall health.
  • Chronic diseases pose a significant health burden on the elderly population.

Purpose of the Study:

  • To evaluate clinical and cardiometabolic markers associated with relative HGS.
  • To investigate the odds of chronic diseases based on relative HGS levels in older adults.

Main Methods:

  • Cross-sectional study of 2451 Korean adults aged 50+ from the Korea National Health and Nutrition Examination Survey.
  • Relative HGS calculated as absolute HGS divided by body mass index (BMI).
  • Multivariate regression analyses used to assess associations between relative HGS tertiles and chronic disease prevalence.

Main Results:

  • Relative HGS was associated with insulin resistance, high-sensitivity C-reactive protein, and HDL cholesterol.
  • Lower relative HGS was linked to higher odds of various chronic diseases in both sexes.
  • Higher odds of hyperlipidemia were observed in women with the lowest relative HGS.

Conclusions:

  • Relative HGS is a practical indicator of overall muscle strength relative to body size.
  • Low relative HGS may predict the development or worsening of chronic conditions.
  • Relative HGS can serve as a cost-effective screening tool for prevalent chronic diseases in the elderly.
Abstract

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