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Complete Coding Sequence of a Pasivirus Found in Swedish Pigs.
Giorgi Metreveli1, Mikael Berg1, Anne-Lie Blomström2
1Department of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Microbiology Resource Announcements
|September 25, 2020
Summary
Researchers identified a novel pasivirus in Swedish pigs with respiratory illness. This virus shares significant genetic similarity with other global pasivirus strains.
Area of Science:
- Veterinary Virology
- Molecular Biology
- Animal Health
Background:
- Pasiviruses are emerging RNA viruses that can affect livestock.
- Respiratory diseases in pigs pose a significant threat to animal agriculture.
- Surveillance of novel pathogens is crucial for disease control.
Purpose of the Study:
- To characterize a newly identified pasivirus from a Swedish pig herd.
- To determine the genetic relatedness of this virus to known pasiviruses.
- To contribute to the understanding of pasivirus diversity and evolution.
Main Methods:
- Viral RNA extraction and sequencing from pig tonsil samples.
- Bioinformatic analysis of the complete coding sequence.
- Comparative sequence analysis with reference pasivirus genomes.
Main Results:
- The complete coding sequence of a novel pasivirus was successfully obtained.
- The identified pasivirus genome showed 75-87% nucleotide and 81-94% amino acid identity to other pasiviruses.
- The virus was detected in a pig from a herd experiencing respiratory disease.
Conclusions:
- This finding expands the known genetic diversity of pasiviruses.
- The characterized Swedish pasivirus is closely related to other global strains.
- Further research is needed to assess the pathogenicity and epidemiological impact of this virus in swine populations.
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