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Isolation and Cultivation of Neural Progenitors Followed by Chromatin-Immunoprecipitation of Histone 3 Lysine 79 Dimethylation Mark
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Histone Variants and Histone Modifications in Neurogenesis

Mengtian Zhang1, Jinyue Zhao1, Yuqing Lv1

  • 1State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China; Innovation Academy for Stem Cell and Regeneration, Chinese Academy of Sciences, 100101 Beijing, China; University of Chinese Academy of Sciences, Beijing 100049, China.

Trends in Cell Biology
|October 4, 2020
PubMed
Summary

Epigenetic regulation, including histone variants and modifications, is crucial for embryonic brain development and neural stem cell fate. Understanding these mechanisms ensures healthy neurogenesis and prevents diseases.

Keywords:
3D genomechromatin remodelingepigenetic regulationneural stem cell

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