Immunoassays in therapeutic drug monitoring

Numerous immunoassay methods are now in routine use for therapeutic drug monitoring of drugs and metabolites. Most methods are homogeneous immunoassays with excellent specificity, accuracy, and precision. In addition, these assays are readily automated, and commercial versions of theses reagents are available with dedicated instrumentation. This report reviews current methods and systems and discusses methodology that has been developed for physician office or other nontraditional settings.