Related Experiment Video
Updated: Dec 6, 2025
An In Vitro Approach to Photodynamic Therapy
Published on: August 17, 2018
Fractional Ablative Laser-Assisted Photodynamic Therapy as Field Treatment for Actinic Keratoses: Our Anecdotal
Jordan V Wang1, Thomas D Griffin2
1Department of Dermatology and Cutaneous Biology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA; drjordanwang@gmail.com.
Abstract:
Actinic keratoses (AKs) are common skin lesions that are often considered to be precancerous markers for the future development of skin cancers. There are various treatment options, including cryotherapy, imiquimod, 5-fluorouracil, curettage, lasers, and photodynamic therapy (PDT). Laser-assisted drug delivery, using the combination of a fractional ablative laser with PDT, is an effective therapy. Our clinical experience with six patients demonstrates that the combination of fractional ablative 2,940nm erbium:yttrium-aluminum-garnet laser with blue light PDT is safe and effective for the field treatment of AKs. (SKINmed. 2020;18:214-216).
