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Pachychoroid: current concepts on clinical features and pathogenesis.

Veronica Castro-Navarro1, Francine Behar-Cohen2,3, Woohyok Chang4

  • 1Hospital General Universitario de Valencia, Valencia, Spain.

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|October 15, 2020
PubMed
Summary

Pachychoroid is a retinal disorder characterized by abnormal choroidal vessels. Identifying its key features aids in differentiating and managing these conditions.

Keywords:
Focal choroidal excavationPachychoroidPachychoroid neovasculopathyPachychoroid pigment epitheliopathyPachydrusenPeripapillary pachychoroid syndrome

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Area of Science:

  • Ophthalmology
  • Retinal Disorders
  • Choroidal Diseases

Background:

  • Pachychoroid describes a phenotype involving choroidal changes in various retinal disorders.
  • Understanding choroidal involvement is crucial for diagnosing and managing these conditions.

Purpose of the Study:

  • To review literature on pachychoroid and its associated pathologies.
  • To identify common features and clinical signs within the pachychoroid spectrum.
  • To outline examination, monitoring, and management strategies.

Main Methods:

  • Literature search of PubMed using keywords related to pachychoroid spectrum.
  • Selection of 157 relevant publications.
  • Identification of key features and clinical characteristics.

Main Results:

  • The hallmark of pachychoroid is hypertrophic choroidal vessels beneath reduced choriocapillaris.
  • Distinguishing uncomplicated from pathological pachychoroid requires additional features.
  • Pathological forms may involve exudation, neovascularization, or retinal atrophy.

Conclusions:

  • Pachychoroid is characterized by large choroidal vessels under deficient choriocapillaris.
  • Understanding pachychoroid spectrum features aids patient management.