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Scheimpflug Densitometry in Keratoconus: A New Method of Visualizing the Cone
Marta Jiménez-García1,2, Sorcha Ní Dhubhghaill1,2, Alejandra Consejo3
1Department of Ophthalmology, Antwerp University Hospital (UZA), Edegem, Belgium.
Cornea
|October 16, 2020
Summary
A novel bright area observed during Scheimpflug densitometry may help delineate keratoconus (KC) progression. This finding could aid in documenting KC staging and potentially detecting disease advancement.
Area of Science:
- Ophthalmology
- Corneal Imaging
- Biomedical Optics
Background:
- Keratoconus (KC) is a progressive corneal ectasia.
- Accurate staging and monitoring of KC are crucial for patient management.
- Current imaging techniques may not fully capture the extent of corneal changes in KC.
Purpose of the Study:
- To report a novel observation during Scheimpflug densitometry analysis in keratoconus.
- To investigate if this observation can delineate the base of the corneal cone.
- To assess the correlation of this finding with KC severity and progression.
Main Methods:
- Scheimpflug densitometry was performed on 90 keratoconus patients and 20 healthy controls.
- Corneal densitometry was analyzed using 1-layer and 2-layer approaches.
- Scans were repeated on the same day and over time to assess consistency and evolution.
Main Results:
- A distinct bright area, corresponding to the cone's location, was observed in 88% of KC cases.
- The characteristics of this bright area correlated with KC severity, being more pronounced in advanced cases.
- This mark was consistent across repeated scans and showed changes over time, even in clinically stable eyes.
Conclusions:
- The observed densitometry mark appears to delineate the most affected zone in keratoconus.
- This finding could serve as a supplementary tool for documenting KC stage.
- Further research is needed to validate its utility in KC detection, progression monitoring, and biomechanical correlation.
