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Related Concept Videos

Other Pulmonary Disorders01:17

Other Pulmonary Disorders

1.4K
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
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Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.01:25

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

3.3K
Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
3.3K
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

291
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
291
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

577
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
577
Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

315
Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
315
COPD: Pathogenesis and Clinical Features01:20

COPD: Pathogenesis and Clinical Features

1.6K
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
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Updated: Dec 5, 2025

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
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Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer

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[Pulmonary involvement in cancers].

Niels Reinmuth1, Sarah-Christin Mavi2

  • 1Abteilung für Thorakale Onkologie, Asklepios Fachkliniken München-Gauting, Robert-Koch-Allee 2, 82131 Gauting, Deutschland.

Der Pneumologe
|October 19, 2020
PubMed
Summary
This summary is machine-generated.

Lung cancer and its treatments can cause lung damage. Pre-existing lung conditions can also worsen cancer outcomes, highlighting the complex relationship between lung health and cancer.

Keywords:
Idiopathic pulmonary fibrosisLung cancerNeoplasm metastasisPulmonary disease, chronic obstructivePulmonary veno-occlusive disease

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Area of Science:

  • Oncology
  • Pulmonology
  • Cancer Therapeutics

Context:

  • The lungs are frequently impacted by primary lung cancer and metastases from other cancers.
  • Recent advancements in cancer treatment have led to a wider array of therapeutic strategies.
  • Pulmonary comorbidities are common in cancer patients and can influence disease progression.

Purpose:

  • To review the multifaceted involvement of the lungs in cancer.
  • To discuss pulmonary side effects of various cancer treatments.
  • To explore the impact of pre-existing lung conditions on cancer prognosis.

Summary:

  • Lung cancer is a prevalent disease with evolving treatment options.
  • Cancer therapies including tyrosine kinase inhibitors, checkpoint inhibitors, CAR T-cell therapy, and radiotherapy can induce pulmonary toxicity.
  • Conditions such as pulmonary veno-occlusive disease, COPD, and idiopathic pulmonary fibrosis are discussed as examples of relevant comorbidities.

Impact:

  • This review underscores the critical need to consider lung health in cancer management.
  • Understanding treatment-related pulmonary toxicities is essential for patient care.
  • Recognizing the interplay between lung comorbidities and cancer prognosis can guide clinical decision-making.