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A case report on granular cell ameloblastoma - A rare histological entity
1Senior Lecturer, Oral Medicine and Radiology, Pushpagiri College of Dental Sciences, Perumthuruthy, Thiruvalla, Kerala, India.
The Indian Journal of Radiology & Imaging
|October 26, 2020
Summary
Granular cell ameloblastoma, a rare aggressive tumor, features transformed cells with granular cytoplasm. This case report details a patient diagnosed with this rare jaw tumor, highlighting its aggressive nature and recurrence potential.
Area of Science:
- Oral pathology
- Oncology
- Granular cell ameloblastoma
Background:
- Ameloblastoma is a common odontogenic tumor, but granular cell ameloblastoma (GCA) is a rare variant (3.5% of cases).
- GCA is characterized by distinct tumor cell cytoplasm transformation.
- This variant exhibits aggressive behavior, including high recurrence rates and metastatic potential.
Observation:
- A case report of a 35-year-old female patient is presented.
- The patient was diagnosed with granular cell ameloblastoma.
- The tumor was located in the right mandible.
Findings:
- Granular cell ameloblastoma exhibits tumor cells with coarse, granular eosinophilic cytoplasm.
- The condition is aggressive with a high propensity for recurrence.
- Metastasis is a possible progression of the disease.
Implications:
- Early diagnosis and aggressive management are crucial for granular cell ameloblastoma.
- Understanding the aggressive nature of GCA is vital for treatment planning.
- Further research into GCA's behavior may improve patient outcomes.
