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Extraction of Flavonoids From Natural Sources Using Modern Techniques
Jaísa Oliveira Chaves1, Mariana Corrêa de Souza1, Laise Capelasso da Silva1
1Multidisciplinary Laboratory in Food and Health, School of Applied Sciences, University of Campinas, Limeira, Brazil.
Frontiers in Chemistry
|October 26, 2020
Summary
Advanced techniques like ultrasound and microwaves offer efficient, eco-friendly flavonoid extraction from plants. This review details modern methods, parameters, and their industrial potential, replacing traditional solvent-intensive processes.
Area of Science:
- Natural Product Chemistry
- Analytical Chemistry
- Green Chemistry
Background:
- Flavonoids, a major class of polyphenols, are abundant in natural sources.
- Traditional extraction methods face challenges with energy, solvent use, and efficiency.
- Market demand and environmental regulations necessitate advanced extraction technologies.
Purpose of the Study:
- To review and compare advanced flavonoid extraction techniques.
- To discuss key parameters influencing extraction efficiency and selectivity.
- To highlight recent trends and the industrial significance of modern methods.
Main Methods:
- Microwave-assisted extraction (MAE)
- Ultrasound-assisted extraction (UAE)
- Pressurized liquid extraction (PLE)
- Supercritical fluid extraction (SFE)
- Pulsed electric field extraction (PEF)
Main Results:
- Advanced techniques demonstrate higher efficiency, selectivity, and reduced consumption of energy and solvents.
- Modern methods offer faster extraction times and increased automation.
- Each technique presents specific advantages and disadvantages regarding operational conditions and scalability.
Conclusions:
- Innovative extraction technologies are crucial for sustainable and efficient flavonoid isolation.
- Understanding extraction parameters is key to optimizing yield and purity.
- These advanced methods hold significant potential for industrial applications in various sectors.

