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Traumatic ulcerative granuloma with stromal eosinophilia
Aashka Sethi1, Akanksha Banga1, Ritika Raja1
1Department of Oral and Maxillofacial Pathology and Oral Microbiology, I.T.S Centre for Dental Studies and Research, Muradnagar, Ghaziabad, Uttar Pradesh, India.
Summary
Oral ulcers can signal systemic issues. Traumatic Ulcerative Granuloma with Stromal Eosinophilia (TUGSE) is a rare oral lesion characterized by numerous eosinophils, requiring careful differential diagnosis.
Area of Science:
- Oral pathology
- Dermatology
- Immunology
Background:
- Oral ulcers are common dental complaints, often linked to local trauma.
- However, oral lesions can indicate underlying systemic diseases.
Observation:
- Two cases of oral ulcers with significant eosinophilic infiltration and lymphoid proliferation were examined.
- Microscopic analysis revealed eosinophils from epithelium to submucosa.
Findings:
- The condition, Traumatic Ulcerative Granuloma with Stromal Eosinophilia (TUGSE), is characterized by abundant eosinophils.
- CD15 immunohistochemistry aids in identifying eosinophils in TUGSE.
- Differential diagnosis is crucial for managing TUGSE.
Implications:
- Recognizing TUGSE is vital for accurate diagnosis and treatment of oral ulcerative lesions.
- This highlights the importance of considering systemic links in oral ulcer presentations.
- Clinicians should be aware of TUGSE in their differential diagnosis of oral lesions.
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