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Cervical mucus changes in relationship to urinary luteinizing hormone.
J Nulsen1, C Wheeler, M Ausmanas
1Department of Obstetrics and Gynecology, Hospital of the University of Pennsylvania, Philadelphia 19104.
Fertility and Sterility
|November 1, 1987
Summary
Detecting the urinary luteinizing hormone (LH) surge accurately predicts peak cervical mucus quality for conception. This finding aids in optimizing timing for fertility treatments and intercourse.
Area of Science:
- Reproductive endocrinology
- Gynecology
- Biomarkers of ovulation
Background:
- Cervical mucus changes are critical indicators of female fertility.
- Accurate identification of the fertile window is essential for assisted reproductive technologies and natural family planning.
Purpose of the Study:
- To correlate the urinary luteinizing hormone (LH) surge with daily cervical mucus parameters.
- To determine the predictive value of urinary LH surge detection for optimal cervical mucus quality.
Main Methods:
- Ten women undergoing infertility evaluation were monitored daily.
- Included twice-daily urinary LH testing, ultrasound, cervical mucus evaluation (modified Insler score), and serum hormone assays (LH, progesterone, estradiol).
Main Results:
- Maximal cervical mucus scores consistently coincided with the urinary LH surge.
- Optimal mucus quality preceded ultrasound-confirmed ovulation by 0–24 hours.
- Mucus scores rapidly decreased post-LH surge.
Conclusions:
- Urinary LH surge detection reliably indicates the period of optimal cervical mucus.
- This method can facilitate precise timing for intercourse, artificial insemination, and postcoital testing.