Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

383
Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
383
Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

231
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
231
Nephrons01:10

Nephrons

5.4K
The kidneys are intricate organs with millions of working units known as nephrons. Each nephron features two major structures: the renal corpuscle, which facilitates blood plasma filtration, and the renal tubule, which handles the glomerular filtrate. Blood supply is directly linked to the nephrons. The renal corpuscle consists of the glomerulus, a capillary network, and the Bowman's capsule, a double-walled epithelial structure that encases the glomerulus. The filtering of blood plasma...
5.4K
Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

389
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
389
Renal Corpuscle01:20

Renal Corpuscle

6.0K
The glomerulus and Bowman's capsule are two essential components of the nephron, which is the functional unit of the kidney. These microscopic structures play a critical role in the process of blood filtration to produce urine.
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
6.0K
Chronic Kidney Disease IV: Nursing Management01:18

Chronic Kidney Disease IV: Nursing Management

178
Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care​.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of...
178

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Empagliflozin versus dapagliflozin for kidney outcomes in stage 3 chronic kidney disease: a propensity score-matched multi-center cohort study.

BMC nephrology·2026
Same author

Diabetic kidney disease, biomarkers, and finerenone.

Diabetes, obesity & metabolism·2026
Same author

Changing the Presentation of Overnight Admissions to Improve Teaching Rounds.

Journal of general internal medicine·2025
Same author

Unravelling the Inflammatory and Metabolic Insights in Subacute Sclerosing Panencephalitis: A Prospective Multimodal Evaluation.

Pediatric neurology·2025
Same author

Radiological Patterns and Clinical Features in Adult-onset Subacute Sclerosing Panencephalitis: a Cross-sectional Study.

Clinical neuroradiology·2025
Same author

Synovial Fluid Proteomic Signatures in Different Subtypes of Juvenile Idiopathic Arthritis.

Scandinavian journal of immunology·2025
Same journal

Primary Care at the Center of America's Mental Health Landscape.

Primary care·2026
Same journal

We Care, and We Will Listen.

Primary care·2026
Same journal

Addressing Sexual Health in Primary Care.

Primary care·2026
Same journal

Diagnosis and Management of Eating Disorders in Adolescents and Young Adults.

Primary care·2026
Same journal

Management of Concomitant Mental Health Conditions in Older Adults with Cognitive Impairment.

Primary care·2026
Same journal

Nonpharmacologic Management of Insomnia Disorder in Primary Care.

Primary care·2026
See all related articles

Related Experiment Video

Updated: Dec 3, 2025

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice
10:31

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice

Published on: May 2, 2025

490

Diabetic Kidney Disease.

Ryan Bonner1, Oltjon Albajrami1, James Hudspeth1

  • 1Section of Nephrology, Department of Medicine, Boston Medical Center and Boston University School of Medicine, 800 Harrison Avenue, G009, Boston, MA 02118, USA.

Primary Care
|October 30, 2020
PubMed
Summary
This summary is machine-generated.

Diabetic kidney disease (DKD) affects 30-40% of diabetes patients, increasing mortality risk. This review covers DKD pathogenesis and management, integrating traditional and new therapies for primary care.

Keywords:
AlbuminuriaChronic kidney diseaseDiabetic kidney diseaseDiabetic nephropathy

More Related Videos

Whole-Kidney Three-Dimensional Staining with CUBIC
04:31

Whole-Kidney Three-Dimensional Staining with CUBIC

Published on: July 18, 2022

4.5K
5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
05:34

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

1.2K

Related Experiment Videos

Last Updated: Dec 3, 2025

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice
10:31

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice

Published on: May 2, 2025

490
Whole-Kidney Three-Dimensional Staining with CUBIC
04:31

Whole-Kidney Three-Dimensional Staining with CUBIC

Published on: July 18, 2022

4.5K
5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
05:34

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

1.2K

Area of Science:

  • Nephrology
  • Endocrinology
  • Public Health

Background:

  • Diabetic kidney disease (DKD) is the leading cause of chronic kidney disease in the U.S.
  • DKD affects 30-40% of individuals with diabetes mellitus.
  • DKD presence significantly increases morbidity and mortality risks.

Purpose of the Study:

  • To review the pathogenesis of diabetic kidney disease.
  • To outline evidence-based management strategies for DKD.
  • To integrate traditional and emerging therapies for DKD.

Main Methods:

  • Literature review of DKD pathogenesis.
  • Analysis of evidence-based strategies for hyperglycemia, hypertension, and albuminuria management.
  • Integration of traditional and novel therapeutic options.

Main Results:

  • Detailed description of DKD pathogenesis.
  • Comprehensive overview of current and emerging DKD management strategies.
  • Emphasis on integrated care approaches.

Conclusions:

  • Understanding DKD pathogenesis is crucial for effective management.
  • Integrated management of hyperglycemia, hypertension, and albuminuria is key.
  • Prioritizing prevention, recognition, and management of DKD in primary care is essential due to its public health burden.