Related Experiment Video
Updated: Dec 2, 2025

05:53
Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
Published on: July 24, 2013
16.9K
Measuring daily functioning in older persons using a frailty index: a cohort study based on routine primary care data
Willeke M Ravensbergen1, Jeanet W Blom1, Andrea Wm Evers2
1Department of Public Health and Primary Care, Leiden University Medical Center, Leiden.
Summary
An electronic frailty index derived from electronic health records (EHRs) does not accurately measure daily functioning in older adults. Further research is needed to develop reliable EHR-based measures for this population.
Area of Science:
- Gerontology
- Health Informatics
- Clinical Research
Background:
- Electronic health records (EHRs) are increasingly utilized for research purposes.
- Extracting complex outcome measures, such as daily functioning, from EHRs remains a challenge.
Purpose of the Study:
- To assess the utility of an electronic frailty index (eFI) derived from routine primary care data as a measure of daily functioning.
- The study focused on community-dwelling older persons aged 75 years and above.
Main Methods:
- A cohort study involving participants from the Integrated Systemic Care for Older People (ISCOPE) trial.
- Daily functioning was measured using the Groningen Activities Restriction Scale (GARS).
- An electronic frailty index (eFI-Utrecht) was computed from EHRs at baseline and 12 months, then compared with GARS.
Main Results:
- The eFI-Utrecht showed responsiveness after major medical events and correlated with age, sex, and living situation.
- However, the correlation between the eFI-Utrecht and GARS for measuring daily functioning was limited.
- Data included 1390 participants (31.4% male, median age 81).
Conclusions:
- The current electronic frailty index is not a suitable measure for daily functioning in older adults.
- New methods are required to effectively extract daily functioning data from routine care data within EHRs for research.
- EHRs need further development to become a valuable data source for geriatric research.
Related Concept Videos
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion
155
In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
155
Drug Dosing: Geriatric Patients
121
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
121

