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Related Experiment Video

Updated: Dec 2, 2025

Sublingual Immunotherapy as an Alternative to Induce Protection Against Acute Respiratory Infections
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[Systemic and local antibiotic therapy for acute sinusitis].

E V Nosulya1, N L Kunelskaya1,2, I A Kim3

  • 1Research Clinical Institute of Otorinolaryngology named after. L.I. Sverzhevsky, Moscow, Russia.

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|November 3, 2020
PubMed
Summary

Fluimucil-Antibiotic demonstrates significant antibacterial activity for acute sinusitis treatment. Its topical application effectively combats biofilms, offering a safe option for clinical practice.

Keywords:
N-acetylcysteineacute sinusitisantibioticsbiofilmrespiratory tract infectionthiamphenicol-glycinate-acetylcysteine

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Area of Science:

  • Medical Microbiology
  • Pharmacology

Background:

  • Acute sinusitis is a common respiratory tract infection.
  • Antibiotic therapy is a cornerstone of treatment.
  • The role of topical antibacterial agents requires further elucidation.

Purpose of the Study:

  • To review modern antibiotic therapy for acute sinusitis.
  • To evaluate the role of topical antibacterials, specifically Fluimucil-Antibiotic.
  • To assess its place in current treatment strategies.

Main Methods:

  • Literature search of PUBMED database.
  • Keywords included: acute sinusitis, antibiotics, thiamphenicol glycinate acetylcysteine, biofilm, respiratory tract infection, N-acetylcysteine.
  • Analysis of published research on Fluimucil-Antibiotic.

Main Results:

  • Fluimucil-Antibiotic exhibits high antibacterial activity.
  • Effective topical use via inhalations, applications, irrigation, and instillations.
  • Demonstrates broad-spectrum action, biofilm destruction, and prevention capabilities.
  • Possesses favorable pharmacokinetics and safety profile.

Conclusions:

  • Fluimucil-Antibiotic shows potential as a topical treatment option for acute sinusitis.
  • Its efficacy against biofilms and safety profile support its use in clinical practice.
  • Further research may solidify its role in managing acute sinusitis.