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A Facile and Eco-friendly Route to Fabricate PolyLactic Acid Scaffolds with Graded Pore Size

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Published on: October 17, 2016

Biopolymer-based Scaffolds for Tissue Engineering Applications.

Hitesh Chopra¹, Sandeep Kumar², Inderbir Singh¹

¹Chitkara College of Pharmacy, Chitkara University, Punjab, India.

Current Drug Targets

|November 4, 2020

Summary

This summary is machine-generated.

This review explores naturally derived biomaterials for tissue engineering. It highlights scaffolds and dermal substitutes, emphasizing the benefits of natural polymers over synthetic ones for improved tissue regeneration.

Keywords:

Scaffolds dermal substitutes hydrogels nanofibers natural polymers tissue engineering

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Area of Science:

Biomaterials Science
Tissue Engineering
Regenerative Medicine

Background:

Tissue engineering utilizes cells and polymers to create functional tissues.
Natural polymers offer advantages like non-immunogenicity and complex structures compared to synthetic alternatives.
Existing drug delivery systems and scaffolds often involve polymers and cells, including nanoparticles, hydrogels, and microspheres.

Purpose of the Study:

To provide an overview of naturally derived biomaterials for tissue engineering.
To focus on scaffolds and dermal substitutes derived from natural sources.
To highlight the advantages of natural polymers in tissue engineering applications.

Main Methods:

Review of existing literature on naturally derived biomaterials.
Analysis of polymer types (natural vs. synthetic) and their properties.
Examination of scaffold design principles and dermal substitute applications.

Main Results:

Natural polymers possess beneficial properties for tissue engineering, such as biocompatibility and structural complexity.
Naturally derived scaffolds and dermal substitutes offer promising alternatives for tissue replacement.
Material selection for scaffolds considers minimizing negative impacts on the human body.

Conclusions:

Naturally derived biomaterials are crucial for advancing tissue engineering.
Scaffolds and dermal substitutes utilizing natural polymers show significant potential for regenerative applications.
Further research into naturally derived materials will enhance tissue engineering strategies.