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Related Concept Videos

Stem Cell Culture01:17

Stem Cell Culture

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Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
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Embryonic Stem Cells00:57

Embryonic Stem Cells

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Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
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Embryonic Stem Cells00:58

Embryonic Stem Cells

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Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
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Source And Potency Of Stem Cells01:27

Source And Potency Of Stem Cells

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Stem cells are undifferentiated cells with extensive self-renewal properties that help them maintain their population during the fetal and adult stages of life. They can specialize in all cell types of the human body. However, their differential potential may vary and can be classified into five types. Stem cells can be (1) Totipotent, (2) Pluripotent, (3) Multipotent, (4) Oligopotent, and (5) Unipotent. Each stem cell has a specific origin; the fertilized egg or zygote is a totipotent cell and...
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Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

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Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
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Distinctive Features of Adult Stem Cells vs Cancer Stem Cells01:18

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A stem cell is an unspecialized cell that can divide without limit as needed and can, under specific conditions, differentiate into specialized cells.
Adult stem cells
Adult stem cells are tissue-specific; hence, they divide to develop the tissue from which they originate. One type of adult stem cell is the epithelial stem cell, which gives rise to the keratinocytes in the multiple layers of epithelial cells in the epidermis of the skin. Adult bone marrow has three distinct types of stem cells:...
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Updated: Dec 2, 2025

Enrichment and Purging of Human Embryonic Stem Cells by Detection of Cell Surface Antigens Using the Monoclonal Antibodies TG30 and GCTM-2
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Enrichment and Purging of Human Embryonic Stem Cells by Detection of Cell Surface Antigens Using the Monoclonal Antibodies TG30 and GCTM-2

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General requirements for stem cells.

Jie Hao1,2, Aijin Ma2,3,4, Lei Wang1,2

  • 1State Key Laboratory of Stem Cell and Reproductive Biology, National Stem Cell Resource Center, Institute for Stem Cell and Regeneration, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.

Cell Proliferation
|November 4, 2020
PubMed
Summary
This summary is machine-generated.

China

Keywords:
detection controlgeneral requirementsquality controlstem cellswaste disposal

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Area of Science:

  • Stem Cell Research and Production Standards
  • Biotechnology and Regenerative Medicine Guidelines

Background:

  • The first comprehensive guidelines for stem cell research and production in China have been established.
  • These standards were jointly developed by experts from the Chinese Society for Stem Cell Research.

Purpose of the Study:

  • To establish unified requirements for stem cell research and production.
  • To promote the ethical and quality-controlled development of stem cells.
  • To accelerate international standardization for clinical applications.

Main Methods:

  • Development of a national standard for stem cells.
  • Inclusion of classification, ethical, quality, and disposal requirements.
  • Revision and release by authoritative Chinese scientific societies.

Main Results:

  • Publication of the 'General requirements for stem cells' standard.
  • Specification of detailed requirements for stem cell handling and production.
  • Establishment of a framework for quality control and detection.

Conclusions:

  • The standard provides a foundational framework for stem cell research and production in China.
  • Implementation of these guidelines is expected to enhance quality and ethical compliance.
  • The initiative aims to align Chinese stem cell practices with international standards for therapeutic applications.