Related Experiment Video
Updated: Dec 2, 2025

Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK
Published on: December 18, 2012
Recurrent Genital Ulcers
Dibyendu Bikash Bhanja1, Abheek Sil1, Avik Panigrahi1
1Department of Dermatology, Venereology, and Leprosy, R.G.Kar Medical College, Kolkata, West Bengal, India.
Papulonecrotic tuberculid is a skin reaction to Mycobacterium tuberculosis. This rare condition, typically on the body, can manifest on the glans penis, causing ulcerated papules and scarring.
Area of Science:
- Dermatology
- Infectious Diseases
- Immunology
Background:
- Papulonecrotic tuberculid is a rare cutaneous manifestation of tuberculosis.
- It results from a hypersensitivity reaction to Mycobacterium tuberculosis.
- Dissemination occurs via hematogenous spread from an internal tuberculous focus.
Observation:
- Characterized by recurrent eruptions of asymptomatic, dusky red papules.
- Lesions progress to ulceration and crusting.
- Healing occurs over weeks, leaving varioliform scars.
Findings:
- While typically affecting extragenital sites, isolated glans penis involvement is exceptionally rare.
- This presentation highlights the diverse clinical spectrum of cutaneous tuberculosis.
- Diagnosis requires high clinical suspicion and correlation with microbiological or histological evidence of tuberculosis.
Implications:
- Understanding this rare presentation is crucial for accurate diagnosis and management of genitourinary tuberculosis.
- Early recognition can prevent complications and facilitate timely treatment of the underlying infection.
- Highlights the importance of considering systemic infections in dermatological diagnoses.
Related Concept Videos
Sexually Transmitted Infections
Drugs for Peptic Ulcer Disease: Sucralfate as Mucosal Protective Agents
In this scenario, mucosal protective agents like sucralfate play an essential role. Sucralfate, a complex of sulfated sucrose and aluminum hydroxide, demonstrates its usefulness in acidic conditions,...
Peptic Ulcer Disease II: Pathophysiology
Damaging agents such as Helicobacter pylori, gastric acid, pepsin, and nonsteroidal anti-inflammatory drugs (NSAIDs) can weaken the mucosal defense, allowing hydrogen ions to infiltrate back and harm epithelial cells.
Peptic Ulcer Disease I: Introduction
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Disorders of the Female Reproductive System

