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Updated: Dec 1, 2025

Whole-Mount Immunofluorescence Staining, Confocal Imaging and 3D Reconstruction of the Sinoatrial and Atrioventricular Node in the Mouse
Published on: December 22, 2020
Anatomy of the Atrioventricular Junction, Atrioventricular Grooves, and Accessory Pathways
1Cardiac Morphology, Imperial College London, Royal Brompton & Harefield NHS Foundation Trust, London SW3 6NP, UK.
Abstract:
Accessory pathways that bypass all or part of the normal atrioventricular conduction system traverse the atrioventricular junction. The atrioventricular junction comprises of a limited septal component and much more extensive right and left parietal components. Its composition forms a plane of insulation between atrial and ventricular myocardium, preventing direct continuity between them. Typical accessory atrioventricular pathways located anywhere along the atrioventricular junction are muscle bundles or may involve muscle around the walls of coronary sinus aneurysms or coronary veins. Increasingly, variants or unusual accessory pathways, some involving an accessory node, are reported in clinical studies.
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