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Related Concept Videos

Chronic Kidney Disease II: Clinical Manifestations01:24

Chronic Kidney Disease II: Clinical Manifestations

380
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
380
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

161
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
161
Chronic Kidney Disease I: Introduction01:25

Chronic Kidney Disease I: Introduction

376
Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
376
Acute Kidney Injury II: Pathophysiology01:29

Acute Kidney Injury II: Pathophysiology

591
Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
591
Acute Kidney Injury III: Clinical Manifestations01:29

Acute Kidney Injury III: Clinical Manifestations

495
Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
495
Acute Kidney Injury I: Introduction01:22

Acute Kidney Injury I: Introduction

331
Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
331

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Articles linked to this work by shared authors, journal, and citation graph.

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Antibiotic resistance of urinary pathogens after kidney transplantation: a 10-year single-center survey in Germany.

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Rare and risky: a unique case of concurrent chronic pulmonary aspergillosis and lemierre syndrome.

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[Angiotensin-converting enzyme 2 (ACE2): role in the pathogenesis of diseases outside of COVID-19].

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[Acute renal failure in COVID-19].

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[Kidney and infectious diseases].

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[COVID-19 and the kidneys].

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Related Experiment Video

Updated: Dec 1, 2025

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice
10:31

Comparative Proteomic Analysis of Whole Kidney, Medulla, and Cortical Tubules in Diabetic Pathogenesis of Kidney Injury in Mice

Published on: May 2, 2025

477

[COVID-19 and the kidneys].

H Rohn1, T Feldkamp2, O Witzke1

  • 1Klinik für Infektiologie, Westdeutsches Zentrum für Infektiologie (WZI) Universitätsmedizin Essen, Universität Duisburg-Essen, Hufelandstr. 55, 45147 Essen, Deutschland.

Der Gastroenterologe : Zeitschrift Fur Gastroenterologie Und Hepatologie
|November 11, 2020
PubMed
Summary
This summary is machine-generated.

The COVID-19 pandemic, caused by SARS-CoV-2, frequently impacts the kidneys. Many patients develop urinary issues and face risks of acute kidney injury.

Keywords:
Acute kidney injuryChronic renal insufficiencyCoronavirusPandemicsSARS-CoV‑2

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Area of Science:

  • Nephrology
  • Infectious Diseases
  • Virology

Context:

  • The COVID-19 pandemic presents a significant global health crisis.
  • Emerging evidence indicates SARS-CoV-2 affects multiple organs beyond the lungs.

Purpose:

  • To highlight the significant renal involvement in COVID-19 patients.
  • To underscore the risk of acute kidney injury in coronavirus disease 2019.

Summary:

  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection leads to widespread organ damage.
  • Kidney complications are common in COVID-19, with many patients exhibiting urinary abnormalities.
  • Patients without pre-existing kidney conditions are at risk for developing acute kidney injury.

Impact:

  • Informing clinicians about the potential for severe renal sequelae in COVID-19.
  • Guiding further research into the mechanisms of SARS-CoV-2-induced kidney damage.
  • Emphasizing the need for vigilant monitoring of kidney function in coronavirus disease 2019 patients.