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Surgical control of Hailey-Hailey disease
P Menz1, I T Jackson, S Connolly
1Section of Plastic and Reconstructive Surgery, Mayo Clinic, Rochester.
British Journal of Plastic Surgery
|November 1, 1987
Summary
Surgical excision with split skin grafting offers the best outcomes for recalcitrant Hailey-Hailey disease. This approach effectively manages refractory lesions, unlike primary suture which can lead to recurrence.
Area of Science:
- Dermatology
- Genodermatoses
- Surgical Oncology
Background:
- Hailey-Hailey disease is a chronic, benign genodermatosis.
- Characterized by recurrent, painful, and malodorous lesions in intertriginous areas.
- Medical therapies are often insufficient for refractory cases.
Purpose of the Study:
- To evaluate the efficacy of surgical excision for Hailey-Hailey disease.
- To compare outcomes of different wound closure techniques.
- To provide evidence for surgical intervention in recalcitrant cases.
Main Methods:
- Review of patient cases undergoing surgical excision for Hailey-Hailey disease.
- Comparison of outcomes between split skin grafting and primary suture.
- Summarization of existing literature on surgical management.
Main Results:
- Split skin grafting yielded superior results, with minimal recurrence and morbidity.
- Primary suture was associated with a higher rate of disease recurrence and persistent morbidity.
- Surgical intervention is effective for managing refractory Hailey-Hailey disease.
Conclusions:
- Surgical excision, particularly when combined with split skin grafting, is a viable and effective treatment for recalcitrant Hailey-Hailey disease.
- This approach offers better long-term control compared to primary suture.
- Surgical management should be considered for patients with severe or medically refractory disease.