Related Experiment Video
Updated: Nov 30, 2025
10:28
Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
Published on: July 24, 2019
15.7K
Modernizing Daily Function Assessment in Parkinson's Disease Using Capacity, Perception, and Performance Measures.
Walter Maetzler1, Lynn Rochester2, Roongroj Bhidayasiri3
1Department of Neurology, Kiel University and University Hospital Schleswig-Holstein, Kiel, Germany.
Movement Disorders : Official Journal of the Movement Disorder Society
|November 16, 2020
Summary
Evaluating daily function in neurological diseases is crucial for assessing therapy success. New digital technologies enable performance measurement, complementing capacity and perception assessments for a comprehensive view.
Area of Science:
- Neurology
- Digital Health
- Rehabilitation Science
Background:
- Disease symptoms, particularly in neurological conditions, significantly impact patients' quality of life, often indirectly through impaired daily function.
- The International Classification of Function, Disability and Health model highlights the link between symptoms, daily function, and quality of life.
- Accurate evaluation of daily function is essential for assessing therapeutic efficacy and developing novel treatments.
Purpose of the Study:
- To discuss the differences and interdependencies between capacity, perception, and performance assessment of daily function.
- To introduce digital technologies as a novel method for measuring daily function performance in patients' home environments.
- To propose future study designs for a comprehensive and validated assessment of daily function in neurological disease patients, using Parkinson's disease as a model.
Main Methods:
- Review and discussion of existing assessment approaches: capacity (clinical assessments) and perception (surveys, patient-reported outcomes).
- Introduction of performance assessment using digital technologies in home settings.
- Analysis of assessment types using Parkinson's disease as a case study.
Main Results:
- Daily function is a complex construct, traditionally measured via capacity and perception.
- Digital technologies offer a new dimension for assessment: performance, capturing real-world daily function.
- Understanding the interplay between capacity, perception, and performance is key for holistic evaluation.
Conclusions:
- Future research protocols should integrate performance assessment alongside capacity and perception measures.
- Digital health technologies provide objective, real-world data on daily function.
- A multi-dimensional approach to assessing daily function is necessary for robust therapeutic evaluation in neurological disorders.
Related Concept Videos
01:15Parkinson's Disease: Overview
1.3K
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
1.3K
01:24Parkinson's Disease: Treatment
777
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
777