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Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
Published on: July 24, 2019
Bridging the global Parkinson's divide: Technology as a structural solution for equitable and brain health-integrated
Roongroj Bhidayasiri1,2, Ruth B Schneider3, Walter Maetzler4
1Chulalongkorn Centre of Excellence for Parkinson's Disease & Related Disorders, Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand.
None:
Parkinson's disease (PD) is the fastest-growing neurodegenerative disorder worldwide, with projections exceeding 25 million people by 2050. Its burden, however, is unevenly distributed. Many low- and middle-income countries face rapidly rising prevalence alongside profound shortages in neurological workforce, infrastructure, and access to specialised care and essential therapies. This global "Parkinson's divide" reflects not merely a funding gap, but a structural mismatch between disease burden and health-system capacity. Traditional clinic-centred models cannot scale to meet this expanding demand.This article argues that technology, when responsibly implemented, offers a structural response to this capacity gap. Telemedicine expands access by decoupling specialist expertise from geography. Wearable and domestic sensor-based technologies extend clinical visibility beyond episodic encounters, capturing real-world fluctuations, mobility changes, falls, and sleep disturbances. Artificial intelligence, positioned as augmented rather than autonomous intelligence, can transform high-volume longitudinal data into actionable insights that support triage, task-sharing, and continuity across distributed care networks. Mobile health platforms further strengthen patient agency through structured self-management and co-designed digital ecosystems.Yet innovation alone is not sufficient. Impact depends on feasibility, interoperability, workforce development, governance, and equity-first design, particularly in resource-constrained settings. Embedded within hybrid care models and life-course brain health frameworks, digital technologies can shift PD management from episodic symptom control toward longitudinal stewardship of function and resilience, helping to convert scarcity into distributed capability and narrow global inequities in Parkinson's care for our future generations.
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