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Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
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Related Experiment Video

Updated: Nov 30, 2025

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
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Acute diverticulitis masquerading as unilateral sciatica-like symptoms.

Victoria Novoselova1, Alexandre Lacasse1

  • 1Department of Internal Medicine, SSM St. Mary's Hospital, St. Louis, Missouri, USA.

Journal of Community Hospital Internal Medicine Perspectives
|November 16, 2020
PubMed
Summary
This summary is machine-generated.

A patient with Systemic Inflammatory Response Syndrome (SIRS) and thigh pain was diagnosed with diverticulitis and a retroperitoneal abscess caused by Bacteroides fragilis. Surgical intervention and antibiotics led to clinical improvement.

Keywords:
Acute diverticulitisleft leg painnon-contrast CT

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Area of Science:

  • Gastroenterology
  • Infectious Diseases
  • Surgical Pathology

Background:

  • Systemic Inflammatory Response Syndrome (SIRS) can be a sign of severe infection.
  • Diverticulitis is a common condition, but complications like abscesses can be serious.
  • Bacteroides fragilis is an anaerobic gram-negative bacterium often found in the gut.

Observation:

  • A 66-year-old female presented with SIRS, severe left thigh pain, and edema.
  • Initial CT scan showed air in the thigh, with no acute intra-abdominal findings.
  • Blood cultures identified Bacteroides fragilis.

Findings:

  • Repeat CT imaging revealed acute diverticulitis with a retroperitoneal abscess extending to the thigh.
  • The abscess was linked to the diverticulitis and Bacteroides fragilis infection.
  • Surgical intervention (sigmoid resection with end-colostomy) was necessary.

Implications:

  • This case highlights a rare but severe complication of diverticulitis.
  • Prompt diagnosis and combined medical-surgical management are crucial for favorable outcomes.
  • Understanding the potential for intra-abdominal infections to cause distant abscesses is important for clinicians.