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[Recurrent polychondritis (report of a case)]
A de S Andrade Filho1, P G de Sena, A L Bittencourt
1Clínica Neurológica, Faculdade de Medicina da Universidade, Federal da Bahia, FAMED-UFBA.
Medicina Cutanea Ibero-Latino-Americana
|January 1, 1987
Summary
Relapsing polychondritis is a rare autoimmune disease. Dapsone treatment effectively managed symptoms and prevented relapses in a patient with this condition.
Area of Science:
- Rheumatology
- Immunology
- Dermatology
Background:
- Relapsing polychondritis (RP) is a rare, episodic, and progressive autoimmune disease characterized by inflammation and destruction of cartilaginous tissues.
- The condition can affect various organs, including the ears, nose, eyes, respiratory tract, and joints, leading to significant morbidity.
Observation:
- A case presentation of a patient with relapsing polychondritis involving atrophic lesions of the nose and ears, alongside conjunctivitis.
- The patient experienced recurrent acute inflammatory episodes characteristic of the disease.
Findings:
- Treatment with dapsone was initiated for 18 months.
- Sustained remission of acute inflammatory episodes was achieved during the dapsone therapy period.
Implications:
- Dapsone appears to be an effective therapeutic option for managing acute flares in relapsing polychondritis.
- This case highlights the potential role of dapsone in the long-term management of relapsing polychondritis, warranting further investigation.