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Related Concept Videos

Liver Regeneration01:24

Liver Regeneration

4.0K
The liver is an important organ in vertebrates that plays an essential role in metabolism. It is also responsible for storing and redistributing nutrients such as carbohydrates, fats, and vitamins in the body. Additionally, the liver releases bile salts which are critical for digesting food and eliminating toxic metabolites from the body.
Cells of Liver
The liver comprises four major types of cells— hepatocytes, stellate, Kupffer, and sinusoidal endothelial cells. The hepatocytes are...
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Tissue Renewal without Stem Cells01:23

Tissue Renewal without Stem Cells

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After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
However, failure of such a system...
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Liver Histology01:27

Liver Histology

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The microscopic anatomy of the liver is a complex and intricate system that comprises numerous structural units known as liver lobules, each of which is comparable in size to a sesame seed. These hexagonal structures consist of plates of liver cells or hepatocytes, which are characterized by their versatility and abundance of cellular apparatus like rough and smooth ER, Golgi apparatus, peroxisomes, and mitochondria.
Hepatocytes perform a variety of essential functions. They secrete...
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Liver Physiology01:30

Liver Physiology

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The liver, an essential organ in the human body, performs over 200 vital functions that can be broadly categorized into metabolic, hematological, endocrine regulation, and bile production.
Metabolic Regulation:
The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of  70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can...
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Overview of Regeneration and Repair01:19

Overview of Regeneration and Repair

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Regeneration and repair processes are critical in healing damages caused by injury, disease, and aging. In regeneration, the damaged tissue is entirely replaced with new growth that restores the original architecture and function. In contrast, tissue repair usually results in a fixed tissue architecture involving scar formation. Scars generally do not reestablish tissue function and may also exhibit structural abnormalities at the injury site.
Regeneration
All animals have varying degrees of...
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[Features of surgical patients of COVID-19 patients].

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[Liver regeneration: resolved and problem issues].

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Related Experiment Video

Updated: Nov 29, 2025

Author Spotlight: Evaluating Therapeutic Strategies to Enhance Liver Regeneration
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Author Spotlight: Evaluating Therapeutic Strategies to Enhance Liver Regeneration

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[Liver regeneration: solved and problem issues].

A N Plekhanov1,2, A I Tovarshinov1

  • 1Buryat State University, Ulan-Ude, Russia.

Khirurgiia
|November 19, 2020
PubMed
Summary

The liver possesses remarkable regenerative capabilities, aiding in treatments for liver diseases like hepatitis and cirrhosis. Understanding liver regeneration is crucial for advancing therapies and addressing related cancers.

Keywords:
livermechanismsregenerationregulationstem cells

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Area of Science:

  • Hepatology and Regenerative Medicine

Background:

  • The liver exhibits significant self-restoration capabilities following injury.
  • The liver maintains functional activity even after substantial damage.

Purpose of the Study:

  • To review current experimental and clinical data on liver regeneration.
  • To summarize methods for stimulating liver regeneration.

Main Methods:

  • Analysis of existing scientific literature on liver regeneration.
  • Review of clinical data related to liver injury and repair.

Main Results:

  • Liver regeneration mechanisms have led to advancements in treating hepatitis, cirrhosis, and liver failure.
  • Understanding liver regeneration is linked to the development of hepatocellular cancer post-cirrhosis.

Conclusions:

  • Significant progress has been made in understanding liver regeneration.
  • Further research is needed to fully elucidate the complexities of liver regeneration.