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Updated: Nov 29, 2025

Analyzing the Size, Shape, and Directionality of Networks of Coupled Astrocytes
Published on: October 4, 2018
Edge-based analysis of networks: curvatures of graphs and hypergraphs
Marzieh Eidi1, Amirhossein Farzam1, Wilmer Leal1,2
1Max Planck Institute for Mathematics in the Sciences, 04103, Leipzig, Germany.
Abstract:
The relations, rather than the elements, constitute the structure of networks. We therefore develop a systematic approach to the analysis of networks, modelled as graphs or hypergraphs, that is based on structural properties of (hyper)edges, instead of vertices. For that purpose, we utilize so-called network curvatures. These curvatures quantify the local structural properties of (hyper)edges, that is, how, and how well, they are connected to others. In the case of directed networks, they assess the input they receive and the output they produce, and relations between them. With those tools, we can investigate biological networks. As examples, we apply our methods here to protein-protein interaction, transcriptional regulatory and metabolic networks.
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