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Potential Anti-Aging Substances Derived from Seaweeds

Lei Cao1, Sang Gil Lee2, Kwon Taek Lim3

  • 1Institute of Marine Life Sciences, Pukyong National University, Busan 48513, Korea.

Marine Drugs
|November 21, 2020
PubMed

Insights

Seaweed compounds show promise in delaying aging by targeting key molecular pathways. Further research in humans is needed to confirm these anti-aging benefits.

Area of Science:

  • Gerontology and Molecular Biology
  • Nutritional Science
  • Marine Biotechnology

Background:

  • Aging is a primary risk factor for numerous chronic diseases, with complex underlying mechanisms.
  • Key molecular pathways, including sirtuin and autophagy, are implicated in aging regulation.
  • Dietary and genetic interventions targeting these pathways can influence lifespan.

Purpose of the Study:

  • To review seaweed-derived bioactive substances with potential anti-aging properties.
  • To explore the cellular and molecular mechanisms of these substances in aging regulation.
  • To summarize findings from studies on cells and animal models.

Main Methods:

  • Literature review of scientific studies on seaweed bioactives and aging.
  • Analysis of research focusing on cellular and molecular anti-aging mechanisms.
  • Inclusion of studies conducted on cell cultures and animal models.

Main Results:

  • Seaweeds are rich in nutrients and bioactive compounds with antioxidant and anti-inflammatory properties.
  • Certain seaweed extracts and compounds modulate aging-regulating pathways.
  • Studies demonstrate lifespan extension in animal models with seaweed-derived interventions.

Conclusions:

  • Seaweed bioactives offer potential for anti-aging interventions by targeting key molecular pathways.
  • Evidence from cell and animal studies supports the anti-aging effects of seaweeds.
  • More research is required, particularly in higher animals and humans, to validate these findings.
Keywords:
anti-agingbioactivemacroalgaeseaweedssenescence

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