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Longitudinal research on the bidirectional association between depression and arthritis
Chaofu Ke1, Yanan Qiao1, Siyuan Liu1
1Department of Epidemiology and Biostatistics, School of Public Health, Medical College of Soochow University, 199 Renai Road, Suzhou, 215123, People's Republic of China.
Social Psychiatry and Psychiatric Epidemiology
|November 22, 2020
Summary
This study found that depression increases the risk of developing arthritis, and arthritis also predicts future depression in older Chinese adults. These findings highlight the bidirectional relationship between these conditions.
Area of Science:
- Gerontology
- Psychiatry
- Rheumatology
Background:
- Limited research exists on the connection between depression and arthritis.
- Existing studies have produced inconsistent findings regarding this relationship.
Purpose of the Study:
- To investigate the bidirectional relationship between depression and arthritis.
- Focus on a middle-aged and elderly Chinese population.
Main Methods:
- Utilized data from the China Health and Retirement Longitudinal Study (CHARLS).
- Assessed baseline depression's association with incident arthritis (Stage I).
- Examined arthritis onset's prediction of future depression (Stage II).
- Employed logistic regression to calculate odds ratios (ORs) and confidence intervals (CIs).
Main Results:
- Depression significantly increased the risk of developing new arthritis cases (OR: 1.56, 95% CI 1.37-1.79).
- Arthritis onset was associated with a higher risk of developing depressive symptoms (OR: 1.64, 95% CI 1.45-1.86).
- Consistent associations were observed across various subgroups (sex, age, income, etc.).
Conclusions:
- Depression onset elevates the risk of incident arthritis.
- Baseline arthritis predicts future depression in middle-aged and elderly Chinese adults.
- Confirms a bidirectional link between depression and arthritis in this demographic.
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