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Oromucosal as an Alternative Method for Administration of Cannabis Products in Rodents
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Cannabinoids in Neurologic Illnesses.

Anup D Patel1

  • 1Neurology, Nationwide Children's Hospital, The Ohio State University College of Medicine, FOB 41.55, 700 Children's Drive, Columbus, OH 43205, USA.

Neurologic Clinics
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Summary
This summary is machine-generated.

Cannabinoids show promise for treating some neurologic conditions like epilepsy. However, more rigorous research is needed to confirm the safety and effectiveness of marijuana-based treatments for most neurological illnesses.

Keywords:
CBDCannabidiolCannabinoidsCannabisMarijuanaMedical cannabisMedical marijuana

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Area of Science:

  • Neurology
  • Pharmacology

Background:

  • Historical use of marijuana for medical purposes.
  • Recent increase in cannabinoid use for neurologic conditions in pediatric and adult patients.

Purpose of the Study:

  • To review the current evidence on the use of cannabinoids for treating neurologic illnesses.
  • To identify gaps in research and areas for future investigation.

Main Methods:

  • Literature review of studies on cannabinoids and neurologic diseases.
  • Analysis of existing data on efficacy and adverse effects.

Main Results:

  • Evidence is limited for most neurologic conditions, with notable exceptions in epilepsy and multiple sclerosis-related spasticity.
  • Insufficient data exists to draw formal conclusions on the efficacy, benefits, and adverse effects of most marijuana-based products for neurologic conditions.

Conclusions:

  • Current data does not support widespread use of cannabinoids for most neurologic conditions.
  • Further high-quality research is essential to establish the potential therapeutic uses and safety profile of cannabinoids in neurology.