Research progress in nanozyme-based composite materials for fighting against bacteria and biofilms

Area of Science:

• Biomaterials Science
• Nanotechnology
• Antimicrobial Research

Background:

• Nanozymes, nanomaterials with enzyme-like activity, show promise as alternatives to antibiotics due to their ability to disrupt bacterial cells.
• The emergence of drug-resistant bacteria necessitates novel therapeutic strategies beyond traditional antibiotics.
• Nanozymes often have inherent defects, leading to the development of composite materials for enhanced functionality.

Purpose of the Study:

• To review the mechanisms and design principles of nanozyme-based composite materials for combating bacteria and biofilms.
• To highlight typical nanozyme types and their applications in fighting bacterial infections and biofilms.
• To discuss the advantages and future prospects of these advanced materials in antimicrobial therapy.

Main Methods:

• Literature review of nanozyme-based composite materials.
• Analysis of mechanisms for combating bacteria and biofilms.
• Categorization of nanozyme types and their synergistic effects in composites.

Main Results:

• Nanozyme-based composites integrate multiple functions, offering intelligent and multi-functional therapeutic models.
• These materials effectively combat bacteria and biofilms, potentially circumventing antibiotic resistance.
• Synergistic effects in composite materials enhance the inherent advantages of nanozymes.

Conclusions:

• Nanozyme-based composite materials represent a promising strategy for future antimicrobial therapies against resistant bacteria and biofilms.
• Further research into challenges and prospects is crucial for optimizing these advanced therapeutic agents.
• The development of multi-functional nanozyme composites is key to addressing the global challenge of antimicrobial resistance.